Nobilis® ND C2 is a live freeze-dried vaccine, indicated for the primary vaccination of chickens at 1 day of age or older against Newcastle Disease.
 
 
PRECAUTIONS
	
Vaccinate healthy chickens only.
	
Do not mix Nobilis® ND C2 with other vaccines.
	
Use according to the number of doses as indicated on the label.
	
Use the entire contents of vial once opened.
	
If the spray method is used for the administration of Nobilis® ND C2, ensure that there is no iron, chlorine or disinfectants in the water.
	
All containers used for reconstitution and administration of Nobilis® ND C2, must be clean and free from rust and traces of detergents and disinfectants.
	
Do not use the contents of damaged vials.
	
It is good vaccination practice when handling vaccines to avoid contact with the eyes, hands and clothing.
	
Wash and disinfect hands and equipment after vaccination.
	
Observe aseptic precautions. Ensure that all vaccination equipment is clean and sterile prior to use.
	
Do not store partially used containers for future use.
DIRECTIONS FOR USE – USE ONLY AS DIRECTED
Do not open and reconstitute Nobilis® ND C2 until ready to start vaccination.
Reconstituted vaccine should be used within 3 hours after reconstitution.
ADMINISTRATION
Nobilis® ND C2 may be administered by spray or eye drop application.
Spray Method
	
Nobilis® ND C2 should be dissolved in cool, clean, non-chlorinated water which is free from iron. The vials of freeze-dried vaccine should be opened under water. The spray apparatus should be free from sediments, corrosion and traces of disinfectants (dedicated for use for vaccination purposes only).
	
The vaccine medicated water should be sprayed evenly over the correct number of chickens, at a distance of 30 to 40 cm, preferably when the chickens are sitting together in dim light.
	
Dissolve 1 000 doses per 250 mℓ to 500 mℓ of water and set the nozzle to produce fine droplets falling like fine rain.
Eye Drop Application
	
Dissolve Nobilis® ND C2 in Diluent Oculo-Nasal (or physiological saline solution) and administer by means of standardised dropper (usually 30 mℓ per 1 000 doses). The drop should be allowed to spread evenly across the surface of the eye. The diluent contains a dye (patent blue) which allows an easy check on the correct vaccination.
	
Do not release the chicken until a swallowing motion is noticed.